Explore SR-9011 dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator data.
SR-9011 is a REV-ERB agonist closely related to SR-9009 (a small molecule, not a peptide), sourced in research for circadian and metabolic studies. Independent data is very thin and oral absorption is poor; it ships as capsules or a powder.
SR-9011 binds REV-ERBα and REV-ERBβ and enhances their constitutive transcriptional-repressor activity at REV-ERB response elements, driving the same general metabolic-program shifts (increased fatty-acid oxidation, mitochondrial-biogenesis effects, altered circadian-gene transcription) demonstrated for SR-9009.[1][4] As with SR-9009, the in-vivo mouse experiments used parenteral (intraperitoneal) administration; the oral bioavailability is published as very limited and the human dose-exposure relationship is essentially uncharacterised.
The founding Solt et al. (Nature 2012) paper introduced SR-9011 alongside SR-9009 as REV-ERB pharmacological tools and demonstrated the same general metabolic and circadian phenotypes in mice via parenteral administration.[1] No human trial has been registered or published.[5] The literature has overwhelmingly favoured SR-9009 for downstream pre-clinical work, so the SR-9011-specific evidence base is even smaller than the (already sparse) SR-9009 literature.
Not FDA-approved. No registered clinical trial. Pre-clinical mouse data only by parenteral administration. WADA-prohibited at all times under S4.5. Research-grade material only.
SR-9011 has a reported half-life of ~4 hours (pre-clinical). The pharmacokinetic reference models an interval of multiple times daily; this is not a measured community cadence or a dosing recommendation. Like its sibling SR-9009, this REV-ERB agonist has a short half-life and clears quickly, so it is dosed multiple times daily. Only rodent data exist. Pharmacokinetic source: Pre-clinical (mouse) data; not characterised in humans. It is catalogued under Other Peptides on WPA.
The WPA community has not yet logged enough SR-9011 calculator sessions to publish dose, vial size, or bacteriostatic water distributions for it. This page therefore covers what is known about the compound itself; the usage charts fill in as researchers run the calculator.
These figures come from anonymized WPA peptide calculator sessions, not verified administrations or unique people. Separate modal inputs do not establish a joint protocol. They are community input statistics — not dosing recommendations, and not medical advice.
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.