Explore Pinealon dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator data.
Pinealon is a synthetic tripeptide (Glu-Asp-Arg) from the Khavinson short-peptide bioregulator program, sourced for neuroprotection and cognitive-aging research as a shorter companion to Epithalon. It ships as a lyophilized powder you reconstitute with bacteriostatic water before use.[1][4]
In the Khavinson framework, Pinealon is proposed to act through direct binding to gene-promoter DNA in cortical neurons and pineal tissue, selectively modulating transcription of genes involved in oxidative-stress defense, neuronal differentiation, and apoptosis regulation.[2] This proposed direct-DNA-binding mechanism is unconventional and has not been independently characterised outside the Khavinson group.
Russian work has reported Pinealon in cell-culture and rodent models of oxidative neuronal stress and in elderly cognitive-decline cohorts, with reported reductions in apoptosis markers and improvements in cognitive-test performance.[3][5] These studies are predominantly single-laboratory and have not been independently replicated outside the Khavinson programme; no Western Phase 2 or 3 trial has been registered.
Not FDA-approved for any indication. Sold in Russia as a non-prescription dietary peptide; research-grade injectable material elsewhere.
Pinealon has a reported half-life of ~30 min (short-peptide estimate). The pharmacokinetic reference models an interval of once daily (in 10–20 day courses); this is not a measured community cadence or a dosing recommendation. As a short Khavinson-type peptide, Pinealon clears from plasma within an hour, so there is no systemic buildup. The bioregulator effect is thought to come from the course as a whole, not a steady blood level. Pharmacokinetic source: No published human PK; Khavinson short-peptide bioregulator estimate. It is catalogued under Anti-Aging Peptides on WPA.
221 Pinealon reconstitution calculations have been logged by the WPA community.
This is the lifetime header population. Each chart and its associated analysis below use their own selected period and denominator; frequency responses are a separate cohort.
These figures come from anonymized WPA peptide calculator sessions, not verified administrations or unique people. Separate modal inputs do not establish a joint protocol. They are community input statistics — not dosing recommendations, and not medical advice.
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.