Melanotan-I Dosage, Reconstitution & Mixing Trends

Explore Melanotan-I (afamelanotide) dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator sessions.

Melanotan-I (afamelanotide) is a potent, MC1-selective alpha-MSH analog approved in implant form as SCENESSE for the prevention of phototoxicity in adults with erythropoietic protoporphyria (EPP). It shares a research origin with Melanotan II at the University of Arizona but followed a fundamentally different commercial path. This data shows the dose amounts, vial sizes, and diluent volumes researchers most commonly select when working with Melanotan-I.

126 Melanotan-I reconstitution calculations have been logged by the WPA community. The most common dose entered is 250mcg (37 calculations). The median dose across all sessions is 300mcg. The most common bacteriostatic water volume is 2mL. The most popular vial size is 10mg (116 sessions). The most common dosing frequency is daily (7x/week) (10 logged protocols), followed by 2x/week (6).

World Peptide Association aggregates anonymized peptide calculator data to show real-world dosing trends, reconstitution volumes, and vial size preferences across the research peptide community.

All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.