Discover HMG dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator sessions.
HMG (Human Menopausal Gonadotropin) is a naturally derived preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity, extracted from the urine of postmenopausal women. It is widely researched in reproductive endocrinology for stimulating follicular development and supporting spermatogenesis. This data captures the dose amounts, vial sizes, and bacteriostatic water volumes researchers most commonly select when setting up their HMG reconstitution protocol.
HMG (Human Menopausal Gonadotropin) is a naturally derived gonadotropin preparation containing both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) biological activity, traditionally extracted from the pooled urine of postmenopausal women — the source of the compound's name, since postmenopausal urine contains elevated gonadotropins due to the loss of ovarian negative feedback.
HMG (menotropin) is a urine-derived mix of the fertility hormones FSH and LH, approved as Menopur and sourced in research for ovulation and ovarian-stimulation studies. It ships as a lyophilized powder reconstituted before use.
HMG provides direct FSH (driving follicular recruitment and growth) and LH (supporting theca-cell androgen production for granulosa-cell aromatisation) — replacing or supplementing endogenous pituitary gonadotropins in patients whose own HPG axis is insufficient or has been suppressed. In men with hypogonadotropic hypogonadism, HMG (or HCG used to provide the LH signal) restores Leydig-cell testosterone production and supports spermatogenesis when combined with FSH activity.
HMG is established standard-of-care for ovulation induction in WHO Group II anovulatory infertility and as part of controlled ovarian stimulation in IVF. In male hypogonadotropic hypogonadism, combined HCG + HMG (or HCG + FSH) restores spermatogenesis in ~80% of treated men, summarised in the Rastrelli meta-analysis. Off-label community use as part of "PCT" protocols after anabolic-androgenic-steroid cycles is widespread but not supported by controlled-trial evidence.
HMG has a reported half-life of ~37 hours (FSH component), and the dose intervals researchers model most often fall around once daily. The FSH component has a long half-life, so daily menotropin dosing builds up over several days to a working level; the LH activity clears faster. It is catalogued under Muscle Peptides on WPA.
3 HMG reconstitution calculations have been logged by the WPA community. The most common dose entered is 2.5mg (2 calculations). The most common bacteriostatic water volume is 2mL. The most popular vial size is 75mg (3 sessions).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.