See GHRP-6 dosage distribution, reconstitution patterns, and vial size preferences from anonymized WPA peptide calculator sessions.
GHRP-6 is a six-amino-acid growth hormone-releasing peptide and ghrelin receptor agonist, one of the earliest GH secretagogues studied, notable for the strong increase in appetite it produces alongside growth hormone release. Like other GHRPs it is dosed at the mcg level and often paired with a GHRH peptide. This data shows the dose amounts, vial sizes, and bacteriostatic water volumes researchers most commonly select when reconstituting GHRP-6.
GHRP-6 is a synthetic hexapeptide growth-hormone-releasing peptide, the first of the GHRP class studied in humans, most often sourced for GH-axis and appetite research. It acts on the ghrelin receptor to trigger a pulse of GH release and a strong appetite signal. It ships as a lyophilized powder you reconstitute with bacteriostatic water before use.
Selective agonist of the ghrelin receptor GHS-R1a expressed in the anterior pituitary (somatotrophs), arcuate nucleus (NPY/AgRP neurons), and several peripheral tissues. In the pituitary, GHS-R1a activation produces a Gαq/PLC/IP3-Ca²⁺ pulse that drives a GH-secretory response that is largely synergistic with GHRH. In the arcuate, GHS-R1a activation drives the canonical orexigenic ghrelin signal.
No regulatory approvals anywhere in the world. Investigated in human pharmacology studies as a GH secretagogue and as a research tool for characterising the GHS-R1a pathway; the ghrelin-axis appetite-stimulation pharmacology made GHRP-6 a useful proof-of-concept compound for the later development of orally bioavailable ghrelin agonists. **Typical dose:** Historical clinical-study doses were 1–2 µg/kg subcutaneous or intravenous, with the dose chosen to produce a roughly maximal GH-secretory response.
GHRP-6 has a reported half-life of ~15–30 min, and the dose intervals researchers model most often fall around once daily (often before bed). Very short-acting — it triggers a GH pulse then clears within minutes, with no buildup. The effect is per-dose, so frequency and timing matter most. It is catalogued under Muscle Peptides on WPA.
47 GHRP-6 reconstitution calculations have been logged by the WPA community. The most common dose entered is 150mcg (18 calculations). The most common bacteriostatic water volume is 2mL. The most popular vial size is 5mg (25 sessions). The most common dosing frequency is daily (7x/week) (4 logged protocols).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.