Explore GHK Basic (copper-free GHK tripeptide) dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator sessions.
GHK Basic is the copper-free form of the GHK tripeptide (Gly-His-Lys), the same naturally occurring sequence found in plasma that declines with age, studied for its proposed roles in skin remodeling, collagen synthesis, and tissue repair. Unlike GHK-Cu, it is supplied without the bound copper ion, which changes how researchers approach reconstitution and concentration. This data shows the dose amounts, vial sizes, and diluent volumes researchers most commonly select when reconstituting GHK Basic.
GHK Basic is the unmodified glycyl-L-histidyl-L-lysine tripeptide, most often sourced for skin-repair and anti-aging research. It is the copper-free parent of GHK-Cu and **lacks the bound copper ion responsible for most published GHK-Cu effects** — see the standalone GHK-Cu entry. It ships as a lyophilized powder you reconstitute with bacteriostatic water before use.
GHK Basic itself has a high binding affinity for copper(II), and a significant proportion of bioactive GHK in plasma exists as the copper-bound complex (GHK-Cu) because the tripeptide opportunistically captures available copper ions. When applied or administered as the unbound tripeptide, GHK Basic's biological activity is partly dependent on subsequent in-vivo copper capture; in copper-replete tissue, the unbound tripeptide may transition to the copper complex and recapitulate GHK-Cu activity, but the timing and efficiency of that transition is not as well-characterised as direct GHK-Cu administration.
The substantial published evidence base for "GHK" is overwhelmingly for the GHK-Cu complex rather than the bare tripeptide — see the standalone GHK-Cu entry for the wound healing, anti-fibrotic, gene-expression-modulating, hair-follicle, and skin-remodelling literature. No major separate clinical program exists for unbound GHK Basic; cosmetic and research-peptide products labelled "GHK" or "GHK Basic" should be regarded as functionally similar to GHK-Cu only to the extent that they capture copper in vivo, and as substantially weaker if that copper capture is incomplete.
GHK Basic has a reported half-life of ~1.5 hours, and the dose intervals researchers model most often fall around once daily. Short half-life — daily dosing clears almost entirely between doses, so the effect is per-dose rather than from accumulated levels. It is catalogued under Skin Peptides on WPA.
16 GHK Basic reconstitution calculations have been logged by the WPA community. The most common dose entered is 1mg (3 calculations). The median dose across all sessions is 500mcg. The most common bacteriostatic water volume is 1mL. The most popular vial size is 10mg (9 sessions).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.