Explore FGL Peptide dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator sessions.
FGL Peptide (FGLoop, FG Loop) is a synthetic peptide derived from the second fibronectin type-III module of the neural cell adhesion molecule (NCAM), engineered to mimic NCAM's binding to the FGF receptor and studied in preclinical models for its proposed effects on synaptic plasticity, memory consolidation, and neuroprotection. This data shows the dose amounts, vial sizes, and bacteriostatic water volumes researchers most commonly select when reconstituting FGL Peptide.
FGL is a 15-amino-acid peptide derived from the second fibronectin type-III module of the neural cell adhesion molecule (NCAM), corresponding to the loop that engages fibroblast growth factor receptor 1 (FGFR1). It was characterised by Elisabeth Bock, Vladimir Berezin, and colleagues at the University of Copenhagen as a synthetic FGFR-agonist surrogate for the NCAM/FGFR neurotrophic interaction.
FGL binds and dimerises FGFR1, triggering the same receptor-tyrosine-kinase cascade — MAPK/ERK and PI3K/Akt — that NCAM uses to drive neurite outgrowth, synaptic plasticity, and neuronal survival, without the cell-adhesion functions of full-length NCAM.
Pre-clinical rodent work has reported pro-cognitive effects in aged rats, neuroprotection in transient cerebral ischemia, and amelioration of amyloid-β-induced deficits in Alzheimer models. No registered human clinical trial has been conducted.
FGL Peptide has a reported half-life of ~2 hours (estimated), and the dose intervals researchers model most often fall around once daily. Short-acting in plasma, so daily dosing works as a fresh pulse with little buildup. The neurotrophic effects are thought to persist longer than the blood level. It is catalogued under Memory Peptides on WPA.
1 FGL Peptide reconstitution calculations have been logged by the WPA community. The most common dose entered is 2.5mg (1 calculations). The most common bacteriostatic water volume is 1mL. The most popular vial size is 5mg (1 sessions).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.