Explore Cortagen dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator sessions.
Cortagen is a short synthetic peptide bioregulator (Ala-Glu-Asp-Pro) from the Khavinson family of organ-specific peptides, derived from a cerebral-cortex extract and studied in Russian-language literature for its proposed effects on nervous-tissue regulation and neuronal recovery. This data shows the dose amounts, vial sizes, and diluent volumes researchers most commonly select when reconstituting Cortagen.
Cortagen is a synthetic Ala-Glu-Asp-Pro (AEDP) tetrapeptide from the Khavinson program, sourced for brain/cortex-tissue and aging research. It ships as a lyophilized powder you reconstitute before use, so the real vendor difference is what the certificate of analysis (COA) shows.
In the Khavinson framework, Cortagen is proposed to act through direct binding to gene-promoter DNA in cortical neurons and supporting glial cells, selectively modulating transcription of genes involved in synaptic protein turnover, neurotrophin signalling, and oxidative-stress defense. This proposed direct-DNA-binding mechanism is unconventional and has not been independently characterised outside the Khavinson group.
Russian single-site studies have reported Cortagen in age-related cognitive decline, recovery after ischaemic stroke, and post-concussive syndrome in elderly patients, with reported improvements in cognitive-test performance and EEG markers versus standard care. These studies are not blinded or placebo-controlled, and no Western Phase 2 or 3 trial has been registered.
Cortagen has a reported half-life of ~few hours (bioregulator estimate), and the dose intervals researchers model most often fall around once daily. Short plasma half-life with daily dosing means no meaningful buildup. The effect of a course is thought to outlast the dosing period. It is catalogued under Memory Peptides on WPA.
4 Cortagen reconstitution calculations have been logged by the WPA community. The most common dose entered is 1mg (4 calculations). The most common bacteriostatic water volume is 2mL. The most popular vial size is 20mg (4 sessions). The most common dosing frequency is daily (7x/week) (2 logged protocols).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.