Explore CJC-1295 (no DAC) dosage trends, reconstitution volumes, and vial size patterns from anonymized WPA peptide calculator data.
CJC-1295 without DAC (also called Mod GRF 1-29) is a GHRH-analog research peptide most often sourced for GH-axis protocols, usually stacked with ipamorelin. It ships as a lyophilized powder you reconstitute with bacteriostatic water before use.
CJC-1295 no-DAC binds the pituitary GHRH receptor on somatotrope cells and triggers pulsatile GH release. Unlike the DAC-conjugated version, the no-DAC variant lacks the maleimide-propionic-acid linker that binds serum albumin — so its half-life remains short (~30 minutes), and dosing is timed to preserve the body's natural GHRH pulse pattern rather than provide continuous receptor activation.
A Phase 1 pharmacokinetic study of CJC-1295 in healthy adults (Teichman et al., JCEM 2006) reported dose-dependent and sustained elevation of IGF-1 with the DAC-conjugated version; the no-DAC variant has not been the subject of a published Phase 1 trial of its own. Research interest persists in combination protocols with selective ghrelin-receptor agonists (e.g. ipamorelin) to drive synergistic, physiologic GH pulses without abolishing endogenous pulsatility.
CJC-1295 (no DAC) has a reported half-life of ~30 min, and the dose intervals researchers model most often fall around once daily (before bed). Without DAC it is gone within about an hour, working as a short pulse that triggers GH release. Timing and frequency matter more than buildup; many users dose more than once a day. It is catalogued under Muscle Peptides on WPA.
369 CJC-1295 (no DAC) reconstitution calculations have been logged by the WPA community. The most common dose entered is 200mcg (84 calculations). The most common bacteriostatic water volume is 2mL. The most popular vial size is 10mg (197 sessions). The most common dosing frequency is daily (7x/week) (28 logged protocols), followed by 5x/week (17).
These figures come from anonymized WPA peptide calculator sessions.
All figures shown are aggregated from anonymized calculator inputs and are provided strictly for independent laboratory research and educational purposes. They are community usage statistics — not dosing recommendations, and not medical advice.